28/07/2022 Food Items
This medication is a muscle relaxant, prescribed as an adjunct to general anesthesia for induction of skeletal muscle relaxation. It is also used for facilitation of management of patients undergoing mechanical ventilation (breathing management); facilitation of tracheal intubation.
Pancuronium dibromide is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.
Pancuronium results in open channel block of embryonic-type nicotinic acetylcholine receptor channels after coapplication of blocker and acetylcholine, characterized by decrease of the time constant of current decay. Pancuronium also results in competitive block of embryonic-type nicotinic acetylcholine receptor channels. Pancuronium increases heart rate, vecuronium and rocuronium produces positive inotropic effects, and vecuronium shortens refractoriness in isolated rat atria.
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