Talk with your doctor about how to start a retinoid program that is right for you. Alpha-hydroxy acids (AHAs) Alpha-hydroxy acids or AHAs are natural based acids and are generally used to exfoliate the skin. They can help soften and smooth skin and reduce discoloration. Medical grade Lumagenex Wrinkle Cream chemical peels that use alpha hydroxy acid penetrate the follicles and help clear cellular debris. This is effective in treating fine lines, wrinkles, skin discoloration, superficial acne, and acne scars or other minor scars. Azelaic acid Azelaic acid is also a natural based acid. It was originally developed to treat mild to moderate acne..