Tuffclassified

Acetazolamide Tablets are an essential pharmaceutical medication used in the treatment of glaucoma, epilepsy, altitude sickness, and various fluid-retention disorders. As a reliable carbonic anhydrase inhibitor, Acetazolamide helps regulate fluid balance, reduce intraocular pressure, and support effective diuretic action. Healthy Life Pharma Pvt. Ltd., a WHO–GMP certified and globally recognized manufacturer in India, produces high-quality Acetazolamide Tablets compliant with IP, BP, and USP standards to meet worldwide therapeutic needs. Therapeutic Uses of Acetazolamide Tablets Acetazolamide exhibits a diverse clinical profile, making it a trusted therapy across multiple medical specialties: Ophthalmology: Effectively lowers intraocular pressure in chronic open-angle glaucoma and secondary glaucoma. Neurology: Used as adjunct therapy in epilepsy due to its stabilizing action on abnormal neuronal firing. Nephrology: Functions as a mild diuretic, aiding in the treatment of metabolic alkalosis and edema associated with heart failure. Pulmonology & High-Altitude Care: Prevents acute mountain sickness by improving respiratory function and enhancing oxygenation at high altitudes. Scientific Action & Pharmacology Acetazolamide is a nonbacteriostatic sulfonamide derivative that reversibly inhibits carbonic anhydrase, an enzyme responsible for bicarbonate and sodium reabsorption. Mechanism of Action: By inhibiting carbonic anhydrase, Acetazolamide reduces hydrogen ion secretion, increases diuresis, and decreases aqueous humor formation—resulting in lower intraocular pressure. Pharmacokinetics: Absorption: Rapid oral absorption with 90–100% bioavailability Protein Binding: ~90% Metabolism: Minimal hepatic metabolism Excretion: Eliminated unchanged via kidneys Half-life: 10–15 hours These properties support its effectiveness across ophthalmic, neurological, renal, and altitude-related conditions.