**Semaglutide for weight loss** is the use of a prescription GLP-1 receptor agonist, together with a reduced-calorie diet and increased physical activity, to help appropriately selected adults with obesity, or with overweight and a weight-related health condition, reduce excess body weight and keep it off over time. Semaglutide is not a supplement and not a shortcut. It is a prescription medication with a boxed warning, defined contraindications, and side effects that require medical follow-up. **A2Z RX LLC** publishes this guide as general education so patients can understand how semaglutide for weight loss works, who may be considered, what the risks are, and what a responsible medical evaluation looks like before any treatment decision is made.